反应详情

A mixture of the intermediate 13 (1.2 g; 5.6 mmol) in ethanol (15 ml), triethylamine (1.5 ml) and 3,5-dimethylthiophenol (1.45 ml; 11 mmol) was heated under reflux for 16 hours. After evaporation under reduced pressure, diethylether (50 ml) was added and the precipitate was filtered off. The intermediate 14 was obtained (1.42 g; 80%) as a colorless solid m.p.=233–235° C.

1. temperaturewas heated
2. temperatureunder reflux for 16 hours
3. customAfter evaporation under reduced pressure, diethylether (50 ml)
4. additionwas added
5. filtrationthe precipitate was filtered off