Sodium ion → tert-butyl (1-{4-[2-(2-aminopyridin-3-yl)-5-{3-[4-(dimethylcarbamoyl)piperidin-1-yl]phenyl}-3H-imidazo[4,5-b]pyridin-3-yl]phenyl}cyclobutyl)carbamate
Reaction equation
[C:62](=[O:63])([O-:64])[O-:65].[CH3:36][N:37]([C:38](=[O:39])[CH:40]1[CH2:41][CH2:42][N:43]([c:46]2[cH:47][c:48]([B:52]3[O:53][C:54]([CH3:55])([CH3:56])[C:57]([CH3:58])([CH3:59])[O:60]3)[cH:49][cH:50][cH:51]2)[CH2:44][CH2:45]1)[CH3:61].[NH2:1][c:2]1[n:3][cH:4][cH:5][cH:6][c:7]1-[c:8]1[n:9][c:10]2[c:11]([n:12][c:13]([Cl:16])[cH:14][cH:15]2)[n:17]1-[c:18]1[cH:19][cH:20][c:21]([C:24]2([NH:28][C:29]([O:30][C:31]([CH3:32])([CH3:33])[CH3:34])=[O:35])[CH2:25][CH2:26][CH2:27]2)[cH:22][cH:23]1.[Na+:66].[Na+:67].[O:68]=[CH:69][N:70]([CH3:71])[CH3:72]>>[NH2:1][c:2]1[n:3][cH:4][cH:5][cH:6][c:7]1-[c:8]1[n:9][c:10]2[c:11]([n:12][c:13](-[c:48]3[cH:47][c:46]([N:43]4[CH2:42][CH2:41][CH:40]([C:38]([N:37]([CH3:36])[CH3:61])=[O:39])[CH2:45][CH2:44]4)[cH:51][cH:50][cH:49]3)[cH:14][cH:15]2)[n:17]1-[c:18]1[cH:19][cH:20][c:21]([C:24]2([NH:28][C:29]([O:30][C:31]([CH3:32])([CH3:33])[CH3:34])=[O:35])[CH2:25][CH2:26][CH2:27]2)[cH:22][cH:23]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-09b375e687ef4a27a5ff2818eeff84ec
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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