反应详情

温度

60 °C

To the compound (500 mg) obtained in Step 1 were added methanol (5 ml) and conc. sulfuric acid (30 μl), and the mixture was stirred overnight at 60° C. To the reaction mixture was further added sodium hydrogen carbonate (250 mg), and the mixture was stirred at room temperature for 2 hrs. After celite filtration of the reaction mixture, the solvent was evaporated to give the title compound as a crude product.

1. stirringthe mixture was stirred at room temperature for 2 hrs
2. filtrationAfter celite filtration of the reaction mixture
3. customthe solvent was evaporated