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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1242424Generated: October 31, 2026

HCID 21638546, compound → HCID 67072407, compound

https://huagongshe.com/reaction/1242424

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 21638546HCID 21638546—
Reactant3-Chloromethyl-2-methyl-6-(4-trifluoromethyl-phenyl)-pyridineHCID 21935751—
ProductHCID 67072407HCID 67072407—

Reaction Steps

In analogy to the procedures described in examples 8A] and 31B], 3-(4-hydroxy-2-methoxy-phenyl)-propionic acid ethyl ester was reacted with 3-chloromethyl-2-methyl-6-(4-trifluoromethyl-phenyl)-pyridine (example 1N]) to give 3-{2-methoxy-4-[2-methyl-6-(4-trifluoromethyl-phenyl)-pyridin-3-ylmethoxy]-phenyl}-propionic acid ethyl ester, which was subsequently saponified to yield the title compound as colorless solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07115611B2
Source datasetuspto-grants-2006_10
ORD IDord-cb7d524260ae4afbaab957cc3a145290
Source noteuspto-grants-2006_10