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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1242482Generated: October 25, 2026

Trifluoroacetic acid → 2-Methyl-6-(4-(trifluoromethyl)phenyl)pyridin-3-amine

https://huagongshe.com/reaction/1242482

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
Reactant[2-Methyl-6-(4-trifluoromethyl-phenyl)-pyridin-3-yl]-carbamic acid tert-butyl esterHCID 67072248—
Product2-Methyl-6-(4-(trifluoromethyl)phenyl)pyridin-3-amineHCID 21935832—

Reaction Steps

In analog to the procedure described in example 5F], [2-methyl-6-(4-trifluoromethyl-phenyl)-pyridin-3-yl]-carbamic acid tert-butyl ester was reacted with trifluoroacetic acid to yield the title compound as colorless solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07115611B2
Source datasetuspto-grants-2006_10
ORD IDord-c97905334bb04f2d99b71115f9ac5d73
Source noteuspto-grants-2006_10