HRID1242507

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：FC(F)(F)Oc1ccc(-c2ccc(CCl)c(C3CC3)n2)cc1

HCID21935654

未命名化合物

HCID86597820

未命名化合物

PRODUCTS

生成物

结构：CCOC(=O)C(C)(C)Oc1ccc(SCc2ccc(-c3ccc(OC(F)(F)F)cc3)nc2C2CC2)cc1C

HCID67072308

未命名化合物

PROCEDURE

实验过程

In analogy to the procedure described in example 142D], 2-(4-acetylsulfanyl-2-methyl-phenoxy)-2-methyl-propionic acid ethyl ester (example 142C]) was reacted with 3-chloromethyl-2-cyclopropyl-6-(4-trifluoromethoxy-phenyl)-pyridine (example 143F]) to give the title compound as colorless oil.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-fc52a2398d61453eb9ef62799a22272c
来源数据集: uspto-grants-2006_10
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07115611B2
来源说明: uspto-grants-2006_10

反应 SMILES

[CH2:1]([O:3][C:4](=[O:20])[C:5]([O:8][C:9]1[CH:14]=[CH:13][C:12]([S:15][C:16](=O)[CH3:17])=[CH:11][C:10]=1[CH3:19])([CH3:7])[CH3:6])[CH3:2].ClCC1[C:24]([CH:40]2[CH2:42][CH2:41]2)=[N:25][C:26]([C:29]2[CH:34]=[CH:33][C:32]([O:35][C:36]([F:39])([F:38])[F:37])=[CH:31][CH:30]=2)=[CH:27][CH:28]=1>>[CH2:1]([O:3][C:4](=[O:20])[C:5]([O:8][C:9]1[CH:14]=[CH:13][C:12]([S:15][CH2:16][C:17]2[C:24]([CH:40]3[CH2:41][CH2:42]3)=[N:25][C:26]([C:29]3[CH:34]=[CH:33][C:32]([O:35][C:36]([F:37])([F:39])[F:38])=[CH:31][CH:30]=3)=[CH:27][CH:28]=2)=[CH:11][C:10]=1[CH3:19])([CH3:7])[CH3:6])[CH3:2]