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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1242511Generated: October 31, 2026

Thionyl Chloride → 5-Chloromethyl-4-methoxymethyl-6-methyl-2-(4-trifluoromethyl-phenyl)-pyrimidine

https://huagongshe.com/reaction/1242511

Reaction equation

Participants

RoleNameHCIDCharge
ReactantThionyl ChlorideHCID 24386—
ReactantHCID 21935612HCID 21935612—
Product5-Chloromethyl-4-methoxymethyl-6-methyl-2-(4-trifluoromethyl-phenyl)-pyrimidineHCID 21935757—

Reaction Steps

In analogy to the procedure described in example 113H], [4-methoxymethyl-6-methyl-2-(4-trifluoromethyl-phenyl)-pyrimidin-5-yl]-methanol and thionylchloride gave the title compound as a light red oil.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07115611B2
Source datasetuspto-grants-2006_10
ORD IDord-6a39d679356b4503b1b278257bca2508
Source noteuspto-grants-2006_10