Diisopropylamine → 1,1,1-Trifluoro-4-(5-fluoro-2-methoxyphenyl)-4-methyl-2-(5-phenylbenzoxazol-2-ylmethyl)pentan-2-ol
Reaction equation
[CH2:1]([Li:2])[CH2:3][CH2:4][CH3:5].[CH2:48]1[O:49][CH2:50][CH2:51][CH2:52]1.[CH3:13][c:14]1[o:15][c:16]2[c:17]([n:18]1)[cH:19][c:20](-[c:23]1[cH:24][cH:25][cH:26][cH:27][cH:28]1)[cH:21][cH:22]2.[CH:6]([NH:7][CH:8]([CH3:9])[CH3:10])([CH3:11])[CH3:12].[F:29][C:30]([C:31]([CH2:32][C:33]([CH3:34])([CH3:35])[c:36]1[c:37]([O:43][CH3:44])[cH:38][cH:39][c:40]([F:42])[cH:41]1)=[O:45])([F:46])[F:47]>>[CH2:13]([c:14]1[o:15][c:16]2[c:17]([n:18]1)[cH:19][c:20](-[c:23]1[cH:24][cH:25][cH:26][cH:27][cH:28]1)[cH:21][cH:22]2)[C:31]([C:30]([F:29])([F:46])[F:47])([CH2:32][C:33]([CH3:34])([CH3:35])[c:36]1[c:37]([O:43][CH3:44])[cH:38][cH:39][c:40]([F:42])[cH:41]1)[OH:45]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-03bff407111f443c99a6c50b95e931d8
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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