HuagongsheHuagongshe Chemistry Print Report · For research reference only
(2S,4EZ)-1-([1,1'-biphenyl]-4-ylcarbonyl)-N'-hydroxy-4-(methoxyimino)-2-pyrrolidinecarboximidamide → HCID 178502619, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (2S,4EZ)-1-([1,1'-biphenyl]-4-ylcarbonyl)-N'-hydroxy-4-(methoxyimino)-2-pyrrolidinecarboximidamide | HCID 90995821 | — |
| Reactant | HCID 178418479 | HCID 178418479 | — |
| Product | HCID 178502619 | HCID 178502619 | 50% |
Reaction Steps
Following the general method as outlined in Example 15, starting from (2S,4EZ)-1-([1,1′-biphenyl]-4-ylcarbonyl)-N′-hydroxy-4-(methoxyimino)-2-pyrrolidinecarboximidamide (Intermediate 8) and 6-hydroxynicotinic-acid, the title compound was obtained in 50% yield (90% purity by HPLC).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07115639B2 |
| Source dataset | uspto-grants-2006_10 |
| ORD ID | ord-aef3e38f9deb4b498faaec26ed1dd904 |
| Source note | uspto-grants-2006_10 |