HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → 116174-33-5
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | 4-[4-(methylthio)phenyl]-4-oxobutanoic acid | HCID 2063715 | — |
| Reactant | HCID 131724811 | HCID 131724811 | — |
| Product | 116174-33-5 | HCID 21916663 | — |
Reaction Steps
A solution of the acid obtained in Step A (19.8 g, 88.1 mmol) in trifluoroacetic acid (68 ml, 881 mmol) is brought to 0° C. and then triethylsilane hydride (35.2 ml, 220 mmol) is added dropwise using a dropping funnel. Stirring is carried out at ambient temperature for 17 hours.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07115752B2 |
| Source dataset | uspto-grants-2006_10 |
| ORD ID | ord-7df6ca34d0864e24b2e68b42a93891e0 |
| Source note | uspto-grants-2006_10 |