HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1242698Generated: October 26, 2026
Thionyl Chloride → 3-[Methyl-(8-{2-[(2-phenylacetyl)amino]ethyl}-2-naphthyl)amino]propanoyl Chloride
https://huagongshe.com/reaction/1242698
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 3-[Methyl(8-{2-[(2-phenylacetyl)amino]ethyl}-2-naphthyl)amino]propanoic Acid | HCID 21917133 | — |
| Product | 3-[Methyl-(8-{2-[(2-phenylacetyl)amino]ethyl}-2-naphthyl)amino]propanoyl Chloride | HCID 21916829 | — |
Reaction Steps
The product obtained in Step B (3 mmol), dissolved in thionyl chloride, is stirred at 60° C. under a stream of nitrogen for one hour. The thionyl chloride is evaporated off under reduced pressure and the residue is dried using a vane pump to yield the title product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US07115752B2 |
|---|
| Source dataset | uspto-grants-2006_10 |
|---|
| ORD ID | ord-9c0dd8f939c4464ba68ebaf844f0053a |
|---|
| Source note | uspto-grants-2006_10 |
|---|
