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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1242790Generated: October 31, 2026

tert-Butyl piperazine-1-carboxylate → tert-Butyl 4-(7H-purin-6-yl)piperazine-1-carboxylate

https://huagongshe.com/reaction/1242790

Reaction equation

Participants

RoleNameHCIDCharge
Reactanttert-Butyl piperazine-1-carboxylateHCID 143452—
Reactant6-ChloropurineHCID 5359277—
Producttert-Butyl 4-(7H-purin-6-yl)piperazine-1-carboxylateHCID 662564992%

Reaction Steps

Step 1: Example 136 was prepared by reacting BOC-piperazine with 6-chloropurine according to Example 1. Yield=92%, ES-MS: (M+H)+ 305.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07115741B2
Source datasetuspto-grants-2006_10
ORD IDord-30adf5b66d3a4b4db61ab7e6ec93024e
Source noteuspto-grants-2006_10