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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1242795Generated: October 30, 2026

Tert-Butyl 4-[6-ethyl-2-(methylethyl)thiopheno[3,2-e]pyrimidin-4-yl]piperazinecarboxylate → 1-{4-[6-Ethyl-2-(methylethyl)thiopheno[3,2-e]pyrimidin-4-yl]piperazinyl}-2-phenylethan-1-one

https://huagongshe.com/reaction/1242795

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTert-Butyl 4-[6-ethyl-2-(methylethyl)thiopheno[3,2-e]pyrimidin-4-yl]piperazinecarboxylateHCID 21062815—
ReactantHCID 21939585HCID 21939585—
Product1-{4-[6-Ethyl-2-(methylethyl)thiopheno[3,2-e]pyrimidin-4-yl]piperazinyl}-2-phenylethan-1-oneHCID 2106261521%

Reaction Steps

Phenylacetamidopiperazine hydrochloride (Example 141) was reacted 2-isopropyl-4-chloro-6-ethylthienopyrimidine (Example 162) according to Example 87. Yield=21%, ES-MS: (M+H)+ 409.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07115741B2
Source datasetuspto-grants-2006_10
ORD IDord-e4709e3cf2564b47bdea5b61bfb8896b
Source noteuspto-grants-2006_10