HCID 21940017, compound → HCID 69497291, compound

Participants

Reaction Conditions

Reaction Steps

10% Palladium—carbon (200 mg) was added to a methanol suspension of N-[4-[(E)-2-(4,5-dihydro-1H-imidazol-2-yl)ethenyl]phenyl][1,1′-biphenyl]-4-carboxamide hydrochloride (80 mg, 0.198 mmol) obtained in Example 124, which was stirred under hydrogen atmosphere at 60° C. for 2 hours. After a catalyst was filtered off, the solvent was distilled out under reduced pressure. Diethyl ether was added to the resulting residue, to give the titled compound (52 mg) as a colorless powder.

Provenance & Evidence