Hydrogen chloride-ethyl acetate → HCID 21939955, compound

Participants

Reaction Steps

4N Hydrogen chloride-ethyl acetate (3 ml) was added to tert-butyl 3-[4-[[(4′-fluoro[1,1′-biphenyl]-4-yl)carbonyl]amino]benzyl]-1-piperidinecarboxylate (150 mg, 0.307 mmol) obtained in Reference Example 81. Two hours later, the solvent was distilled out under reduced pressure. Diisopropyl ether was added to the residue, to give the titled compound (115 mg) as a colorless powder.

Provenance & Evidence