Hydrogen chloride-ethyl acetate → HCID 21939994, compound

Participants

Reaction Steps

4N Hydrogen chloride-ethyl acetate (3 ml) was added to tert-butyl 3-[4-[[(4′-chloro[1,1′-biphenyl]-4-yl)carbonyl]amino]benzyl]-1-piperidinecarboxylate (150 mg, 0.297 mmol)obtained in Reference Example 82. Two hours later, the solvent was distilled out under reduced pressure. Diisopropyl ether was added to the residue, to give the titled compound (73.3 mg) as a colorless powder.

Provenance & Evidence