Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hydrochloric Acid → 2-[1-Ethyl-3-(methylamino)propoxy]-6-(trifluoromethyl)-3-pyridinecarbonitrile hydrochloride
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hydrochloric Acid | HCID 313 | — |
| 반응물 | 1,1-Dimethylethyl [3-[[3-cyano-6-(trifluoromethyl)-2-pyridinyl]oxy]pentyl]methylcarbamate | HCID 69655923 | — |
| 용매 | 1,4-Dioxane | HCID 31275 | — |
| 생성물 | 2-[1-Ethyl-3-(methylamino)propoxy]-6-(trifluoromethyl)-3-pyridinecarbonitrile hydrochloride | HCID 21928359 | — |
반응 단계
1,1-Dimethylethyl [3-[[3-cyano-6-(trifluoromethyl)-2-pyridinyl]oxy]pentyl]methylcarbamate (170 mg) was dissolved in 4M HCl in dioxane (10 ml). The resulting solution was stirred at room temperature for 2 h, then the solvent was evaporated. The residue was recrystallised from diethyl ether/ethanol to give the title compound (100 mg) as a white solid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07119109B2 |
| 출처 데이터셋 | uspto-grants-2006_10 |
| ORD ID | ord-c13c3f2294f74c538fd20619a6744d2a |
| 출처 메모 | uspto-grants-2006_10 |