Hydrochloric Acid → HCID 21928330, compound

HRID 1243610Notes

Reaction equation

HRID 1243610 reaction equation
[C:1]([C:3]1[C:4]([S:10][CH:11]([CH2:23][CH3:24])[CH2:12][CH2:13][N:14](C)[C:15](=O)OC(C)(C)C)=[N:5][C:6]([CH3:9])=[CH:7][CH:8]=1)#[N:2].[ClH:25]>O1CCOCC1>[ClH:25].[CH2:23]([CH:11]([S:10][C:4]1[C:3]([C:1]#[N:2])=[CH:8][CH:7]=[C:6]([CH3:9])[N:5]=1)[CH2:12][CH2:13][NH:14][CH3:15])[CH3:24]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 69656724HCID 69656724, compound

Product 1

HCID 21928330HCID 21928330, compound

Reagents, catalysts & solvents 1

HCID 312751,4-DioxaneSolvent

Procedure

1,1-Dimethylethyl [3-[(3-cyano-6-methyl-2-pyridinyl)thio]pentyl]methylcarbamate (110 mg) was dissolved in 4M HCl in dioxane (10 ml). The resulting solution was stirred at room temperature for 1 h, then the solvent was evaporated off. The residue was recrystallised from diethyl ether/ethanol to give the title compound (90 mg) as a white solid.

Workup

  1. customthe solvent was evaporated off
  2. customThe residue was recrystallised from diethyl ether/ethanol

Sources & evidence

ORD record
ord-912f5fb5417a45dea6d1cb2399b37767
Source dataset
uspto-grants-2006_10
Patent number
US07119109B2

Reaction notes

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