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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1243626Generated: October 31, 2026

5-(Trifluoromethyl)-1,3-oxazol-2-amine → rac-4-fluoro-N-(5-(trifluoromethyl)oxazol-2-yl)-9H-xanthene-9-carboxamide

https://huagongshe.com/reaction/1243626

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-(Trifluoromethyl)-1,3-oxazol-2-amineHCID 21928627—
Reactant(RS)-4-fluoro-9-xanthene-carboxylic acidHCID 21928630—
Productrac-4-fluoro-N-(5-(trifluoromethyl)oxazol-2-yl)-9H-xanthene-9-carboxamideHCID 10362260—

Reaction Steps

The title compound, white solid, m.p. 228° C. and MS: m/e=379.2 (M+H+) is prepared in accordance with the general method of example 3c from 5-trifluoromethyl-oxazol-2-ylamine and (RS)-4-fluoro-9-xanthene-carboxylic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07119113B2
Source datasetuspto-grants-2006_10
ORD IDord-fd9850b876154aeda03c212164707780
Source noteuspto-grants-2006_10