HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → HCID 21930688, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | Bromomethyl tricyclo[3.3.1.13,7]dec-1-yl ketone | HCID 197820 | — |
| Reactant | Tert-butyl malonate | HCID 21883978 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 21930688 | HCID 21930688 | — |
Reaction Steps
To tert-butyl malonate was added, in THF, an equimolar amount of sodium hydroxide. To this mixture was added bromomethyl adamantyl ketone, and the mixture was stirred for 3 hours. The salt precipitated was filtered off, and the filtrate was concentrated to obtain di-tert-butyl 2-((1-adamantyl)carbonyl-methyl)malonate (ADTB).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07119156B2 |
| Source dataset | uspto-grants-2006_10 |
| ORD ID | ord-f7eb8a2e89c94ce78b1a56b03ea86aad |
| Source note | uspto-grants-2006_10 |