Ethyl 3-(N,N-dimethylamino)acrylate → HCID 69594764, compound

Participants

Reaction Conditions

Reaction Steps

0.27 g of 2-oxo-5,5-diphenylcyclohex-3-enylamine hydrochloride is dissolved in 3 cm3 of methanol and the solution is cooled to a temperature in the region of 0° C. 0.14 cm3 of ethyl 3-dimethylaminoacrylate is added to the preceding solution and the mixture is stirred for about 60 hours at a temperature in the region of 20° C. The reaction mixture is then concentrated to dryness under reduced pressure (13 kPa) and the residue is taken up in 12 cm3 of tetrahydrofuran. 0.3 g of ethyl 3-(2-oxo-5,5-diphenylcyclohex-3-enylamino)acrylate is obtained in the form of an orange-coloured oil, which is used without further modification in subsequent syntheses and the characteristics of which are as follows:

Provenance & Evidence