Dichloromethane → HCID 21931952, compound

HRID 1243924Notes

Reaction equation

HRID 1243924 reaction equation
F[C:2]1[CH:16]=[CH:15][C:5]([O:6][CH:7]([OH:14])[C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)=[CH:4][CH:3]=1.C(N(CC)CC)C.[C:24](Cl)(=[O:26])[CH3:25].C(Cl)[Cl:29]>>[C:24]([O:14][CH:7]([O:6][C:5]1[CH:15]=[CH:16][C:2]([Cl:29])=[CH:3][CH:4]=1)[C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1)(=[O:26])[CH3:25]

Participants

5

Reactant 4

HCID 6344DichloromethaneHCID 6367Acetyl chlorideHCID 8471TriethylamineHCID 54066592HCID 54066592, compound

Product 1

HCID 21931952HCID 21931952, compound

Procedure

To a solution of compound 26 (21.8 g, 0.1 M) and triethylamine (14 mL, 0.1 M) in 300 mL CH2Cl2, acetyl chloride (8 g, 0.102 M) was added at room temperature. The mixture was kept at room temperature for 18 h, then washed with water, dried over Na2SO4, concentrated to afford 27.3 g of 4-chlorophenoxybenzyl acetate 32 as an oil.

Workup

  1. washwashed with water
  2. dry with materialdried over Na2SO4
  3. concentrationconcentrated

Sources & evidence

ORD record
ord-1fa3402ea5634d9e830e0cac8198a760
Source dataset
uspto-grants-2006_10
Patent number
US07119214B2

Reaction notes

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