HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl 1H-imidazol-1-ylacetate → Imidazole-1-acetic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl 1H-imidazol-1-ylacetate | HCID 557332 | — |
| Solvent | Water | HCID 962 | — |
| Product | Imidazole-1-acetic acid | HCID 656129 | 97% |
Reaction Steps
Under nitrogen, refluxed 300 mg of imidazol-1-yl-acetic acid methyl ester in 12 ml of H2O for 6 hours. Evaporated in vacuo after cooling to yield 240 mg of white solid (97%) 1H NMR (400 MHz, CD3OD) δ 4.79 (2H, s), 7.41 (1H, s), 7.48 (1H, s), 8.70 (1H, s).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07119207B2 |
| Source dataset | uspto-grants-2006_10 |
| ORD ID | ord-3a5128c9c65f4b478ab52fac33be8a2b |
| Source note | uspto-grants-2006_10 |