HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-Methoxy-1-methyl-2-oxo-1,2,3,4-tetrahydroquinoline-7-carbaldehyde → 7-[(6-Ethyl-2-phenyl-piperidin-3-ylamino)-methyl]-6-methoxy-1-methyl-3,4-dihydro-1H-quinolin-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-Methoxy-1-methyl-2-oxo-1,2,3,4-tetrahydroquinoline-7-carbaldehyde | HCID 10125178 | — |
| Reactant | 6-Ethyl-2-phenyl-piperidin-3-ylamine | HCID 21931648 | — |
| Reactant | HCID 44196399 | HCID 44196399 | — |
| Reactant | (2R,3R,6R)-6-Ethyl-2-phenyl-piperidin-3-ylamine | HCID 69654712 | — |
| Product | 7-[(6-Ethyl-2-phenyl-piperidin-3-ylamino)-methyl]-6-methoxy-1-methyl-3,4-dihydro-1H-quinolin-2-one | HCID 21931737 | — |
Reaction Steps
By a procedure similar to the previous examples 9 and 9A: prepared through the reaction of 6-ethyl-2-phenyl-piperidin-3-ylamine [or (2S,3S,6S)-6-ethyl-2-phenyl-piperidin-3-ylamine or (2R,3R,6R)-6-ethyl-2-phenyl-piperidin-3-ylamine] with 6-Methoxy-1-methyl-2-oxo-1,2,3,4-tetrahydro-quinoline-7-carbaldehyde.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07119207B2 |
| Source dataset | uspto-grants-2006_10 |
| ORD ID | ord-5f8f868177944cf299ff8d532684a7be |
| Source note | uspto-grants-2006_10 |