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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1244075Generated: October 30, 2026

Oxygen → 7-[((2S,3S,6S)-6-Isopropyl-2-phenyl-piperidin-3-ylamino)-methyl]-6-methoxy-1-methyl-3,4-dihydro-1H-[1,5]naphthyridin-2-one

https://huagongshe.com/reaction/1244075

Reaction equation

Participants

RoleNameHCIDCharge
ReactantOxygenHCID 977—
Reactant6-Isopropyl-2-phenyl-piperidin-3-ylamineHCID 21931715—
Reactant2-Methoxy-5-methyl-6-oxo-5,6,7,8-tetrahydro-[1,5]naphthyridine-3-carbaldehydeHCID 21931764—
Product7-[((2S,3S,6S)-6-Isopropyl-2-phenyl-piperidin-3-ylamino)-methyl]-6-methoxy-1-methyl-3,4-dihydro-1H-[1,5]naphthyridin-2-oneHCID 69654934—

Reaction Steps

By a procedure similar to the previous examples 9 and 9A: prepared through the reaction of 6-isopropyl-2-phenyl-piperidin-3-ylamine with 2-Methoxy-5-methyl-6-oxo-5,6,7,8-tetrahydro-[1,5]naphthyridine-3-carbaldehyde. Mass spectrum calcd for C25 H34 N4 O2 (M+1) 423; found 423.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07119207B2
Source datasetuspto-grants-2006_10
ORD IDord-f6489f4b66d74eb09225d708569fead5
Source noteuspto-grants-2006_10