HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cesium carbonate → 1-(but-3-en-1-yl)pyrrolidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cesium carbonate | HCID 10796 | — |
| Reactant | Homoallyl bromide | HCID 21241 | — |
| Reactant | Pyrrolidine | HCID 31268 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 1-(but-3-en-1-yl)pyrrolidine | HCID 250707 | — |
Reaction Conditions
| Temperature | 120 °C |
|---|
Reaction Steps
4-Bromo-but-1-ene (81 mg, 0.6 mmol) was added dropwise to a stirred suspension of pyrrolidine (50 μL, 0.6 mmol) and Cs2CO3 (196 mg, 0.6 mmol) in 1 mL DMF. The mixture was heated to 120° C. using microwave for 20 min, then filtered and used for the next step directly without purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07119205B2 |
| Source dataset | uspto-grants-2006_10 |
| ORD ID | ord-652fca441a4a47c7b72b35d2c4ab736f |
| Source note | uspto-grants-2006_10 |