HuagongsheHuagongshe Chemistry Print Report · For research reference only
Glycolic Acid → HCID 178423363, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Glycolic Acid | HCID 757 | — |
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 6-Methylpyridine-2,3-diamine | HCID 2734420 | — |
| Solvent | Chloroform | HCID 6212 | — |
| Product | HCID 178423363 | HCID 178423363 | — |
Reaction Steps
In accordance with scheme 4, a corresponding 2,3-diamino-6-methyl pyridine (R5=methyl, XV) and glycolic acid were heated at 150° C. for about 1 h. The residue was suspended in chloroform and treated with thionyl chloride for about 4 h. After workup 2-chloromethyl-5-methyl-3H-imidazo[4,5-b]pyridine hydrochloride (XVII) was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07122545B2 |
| Source dataset | uspto-grants-2006_10 |
| ORD ID | ord-d3fa850db4f44546a86a78d9daa1e420 |
| Source note | uspto-grants-2006_10 |