HCID 11305377, compound → HCID 11352458, compound

Participants

Reaction Conditions

Reaction Steps

g 5-Chloro-3-methoxymethyl-2-(4-methoxy-7-morpholin-4-yl-benzothiazol-2-yl)-3H-imidazo[4,5-b]pyridine (0.22 mmol) were dissolved in morpholine (5 ml) in an autoclave and heated to 150° C. for 16 h. The residue was triturated in water whereupon a precipitate formed, which was isolated and dried in vacuo. 0.074 g 3-methoxymethyl-2-(4-methoxy-7-morpholin-4-yl-benzothiazol-2-yl)-5-morpholin-4-yl-3H-imidazo[4,5-b]pyridine (66%) were obtained as a yellow solid; M.p.: 126–128° C.

Provenance & Evidence