HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl iodide → 4-Methoxy-7-morpholin-4-yl-benzothiazole-2-carboximidothioic acid methyl ester hydroiodide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl iodide | HCID 6328 | — |
| Reactant | 4-Methoxy-7-morpholin-4-yl-benzothiazole-2-carbothioic acid amide | HCID 21919254 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 4-Methoxy-7-morpholin-4-yl-benzothiazole-2-carboximidothioic acid methyl ester hydroiodide | HCID 69184072 | 51% |
Reaction Steps
g 4-Methoxy-7-morpholin-4-yl-benzothiazole-2-carbothioic acid amide and 20.3 ml iodomethane in 100 ml tetrahydrofurane were stirred at room temperature for three days. The resulting precipitate was filtered to yield 0.74 g (51%) 4-methoxy-7-morpholin-4-yl-benzothiazole-2-carboximidothioic acid methyl ester hydroiodide; M.p.: 169–171° C.; MS (ISP): m/e=324 (M+H+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07122545B2 |
| Source dataset | uspto-grants-2006_10 |
| ORD ID | ord-4e438033d51b46e4b3cc65f3e1105296 |
| Source note | uspto-grants-2006_10 |