HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Oxo-2-(thiophen-2-yl)acetaldehyde → 3-(4-Fluoro-benzyl)-7-thiophen-2-yl-[1,2,4]triazolo[4,3-b][1,2,4]triazine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Oxo-2-(thiophen-2-yl)acetaldehyde | HCID 5272214 | — |
| Reactant | 5-[(4-Fluorophenyl)methyl]-4H-1,2,4-triazole-3,4-diamine | HCID 21919322 | — |
| Product | 3-(4-Fluoro-benzyl)-7-thiophen-2-yl-[1,2,4]triazolo[4,3-b][1,2,4]triazine | HCID 21919314 | — |
Reaction Steps
General procedure A was followed with the reaction of oxo-thiophen-2-yl-acetaldehyde and 5-(4-fluoro-benzyl)-[1,2,4]triazole-3,4-diamine to provide 3-(4-fluoro-benzyl)-7-thiophen-2-yl-[1,2,4]triazolo[4,3-b][1,2,4]triazine and 3-(4-fluoro-benzyl)-6-thiophen-2-yl-[1,2,4 ][triazolo 1,2,4,-b][1,2,4]triazine (example 5).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07122548B2 |
| Source dataset | uspto-grants-2006_10 |
| ORD ID | ord-e930fc685e644cfeb3e55267d405ad9f |
| Source note | uspto-grants-2006_10 |