HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(4-Bromophenyl)-2-oxoacetaldehyde → 6-(4-Bromo-phenyl)-3-(4-fluoro-benzyl)-[1,2,4]triazolo[4,3-b][1,2,4]triazine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(4-Bromophenyl)-2-oxoacetaldehyde | HCID 233586 | — |
| Reactant | 5-[(4-Fluorophenyl)methyl]-4H-1,2,4-triazole-3,4-diamine | HCID 21919322 | — |
| Product | 6-(4-Bromo-phenyl)-3-(4-fluoro-benzyl)-[1,2,4]triazolo[4,3-b][1,2,4]triazine | HCID 11451912 | — |
| Product | 7-(4-Bromo-phenyl)-3-(4-fluoro-benzyl)-[1,2,4]triazolo[4,3-b][1,2,4]triazine | HCID 21919324 | — |
Reaction Steps
General procedure A was followed with the reaction of (4-bromo-phenyl)-oxo-acetaldehyde and 5-(4-fluoro-benzyl)-[1,2,4]triazole-3,4-diamine to provide 7-(4-bromo-phenyl)-3-(4-fluoro-benzyl)-[1,2,4]triazolo[4,3-b][1,2,4]triazine and 6-(4-bromo-phenyl)-3-(4-fluoro-benzyl)-[1,2,4]triazolo[4,3-b][1,2,4]triazine (example 5).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07122548B2 |
| Source dataset | uspto-grants-2006_10 |
| ORD ID | ord-b4f892dfe4234f30a77ff6520578667a |
| Source note | uspto-grants-2006_10 |