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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 124481Generated: October 26, 2026

Ammonium → Tert-butyl 4-(4-chloro-3-fluorophenyl)-4-cyanopiperidine-1-carboxylate

https://huagongshe.com/reaction/124481

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAmmoniumHCID 223—
ReactantChlorideHCID 312—
ReactantSodium ionHCID 923—
ReactantDimethylformamideHCID 6228—
ReactantIodide IonHCID 30165—
Reactant15-Crown-5HCID 36336—
ReactantHydrideHCID 166653—
Reactant2-(4-Chloro-3-fluorophenyl)acetonitrileHCID 3804414—
ReactantN-BOC-N,N-Bis(2-chloroethyl)amineHCID 11230235—
ProductTert-butyl 4-(4-chloro-3-fluorophenyl)-4-cyanopiperidine-1-carboxylateHCID 66618032—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (2/10)
ORD IDord-0d8c6d81cd5a4550b10e1120ef06ed99
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (2/10)