Ammonium → Tert-butyl 4-(4-chloro-3-fluorophenyl)-4-cyanopiperidine-1-carboxylate
Reaction equation
[CH2:14]1[O:15][CH2:16][CH2:17][O:18][CH2:19][CH2:20][O:21][CH2:22][CH2:23][O:24][CH2:25][CH2:26][O:27][CH2:28]1.[Cl-:45].[Cl:31][CH2:32][CH2:33][N:34]([C:35]([O:36][C:37]([CH3:38])([CH3:39])[CH3:40])=[O:41])[CH2:42][CH2:43][Cl:44].[Cl:3][c:4]1[c:5]([F:13])[cH:6][c:7]([CH2:10][C:11]#[N:12])[cH:8][cH:9]1.[H-:2].[I-:29].[NH4+:46].[Na+:1].[Na+:30].[O:47]=[CH:48][N:49]([CH3:50])[CH3:51]>>[Cl:3][c:4]1[c:5]([F:13])[cH:6][c:7]([C:10]2([C:11]#[N:12])[CH2:32][CH2:33][N:34]([C:35]([O:36][C:37]([CH3:38])([CH3:39])[CH3:40])=[O:41])[CH2:42][CH2:43]2)[cH:8][cH:9]1Participants
10
Reactant 9
Product 1
Sources & evidence
- ORD record
- ord-0d8c6d81cd5a4550b10e1120ef06ed99
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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