HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1244897Generated: October 31, 2026
Hydrochloric Acid → HCID 178478586, compound
https://huagongshe.com/reaction/1244897
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Dichloromethane methanol ammonium hydroxide | HCID 21896990 | — |
| Reactant | N-(2-aminoethyl)-2-chloro-9-cyclopentyl-9H-purin-6-amine | HCID 21922924 | — |
| Reactant | HCID 178511674 | HCID 178511674 | — |
| Solvent | 1-Butanol | HCID 263 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 178478586 | HCID 178478586 | — |
Reaction Steps
160 mg of the product obtained in Stage 1 of Example 7, 10 ml of butanol and 690 mg of trans-1,4-diaminocyclohexane are mixed together, the reaction medium is heated to approximately 150° C. for approximately 4 days. After chromatography on silica eluting with methylene chloride/methanol/ammonium hydroxide in a proportion of 70/25/05 salification is carried out with a 1.4N solution of HCl in ethanol and in this way 60 mg of expected product is obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US07122669B1 |
|---|
| Source dataset | uspto-grants-2006_10 |
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| ORD ID | ord-65c222f9e2864e3e9ef07b9551562c0c |
|---|
| Source note | uspto-grants-2006_10 |
|---|
