HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Chloropyridine-2-carboxylic acid → HCID 69610175, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Chloropyridine-2-carboxylic acid | HCID 230890 | — |
| Reactant | (S)-Methyl 3-([1,1'-biphenyl]-4-yl)-2-aminopropanoate | HCID 15714801 | — |
| Product | HCID 69610175 | HCID 69610175 | 85% |
Reaction Steps
3-Biphenyl-4-yl-(2S)-[(4-chloro-pyridine-2-carbonyl)-amino]-propionic acid methyl ester (1.26 g, 85%) was prepared by following general procedure A from commercially available 4-chloro picolinic acid (0.7 g, 4.4 mmol) and (2S)-amino-3-biphenyl-4-yl-propionic acid methyl ester (1.0 g, 3.9 mmol).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07122580B2 |
| Source dataset | uspto-grants-2006_10 |
| ORD ID | ord-725a01fd0b174f32a5f19108a909d419 |
| Source note | uspto-grants-2006_10 |