HCID 21919190, compound → HCID 21919141, compound

HRID 1245162Notes

Reaction equation

HRID 1245162 reaction equation
[CH3:1][O:2][C:3]1[C:4]([CH3:34])=[C:5]([C:25]([O:32][CH3:33])=[C:26]([O:30][CH3:31])[C:27]=1[O:28][CH3:29])[CH2:6][C:7]1[CH:16]=[CH:15][C:10]([C:11]([O:13][CH3:14])=[O:12])=[C:9]([O:17]CC2C=CC=CC=2)[CH:8]=1.[H][H]>CO.[C].[Pd]>[CH3:1][O:2][C:3]1[C:4]([CH3:34])=[C:5]([C:25]([O:32][CH3:33])=[C:26]([O:30][CH3:31])[C:27]=1[O:28][CH3:29])[CH2:6][C:7]1[CH:16]=[CH:15][C:10]([C:11]([O:13][CH3:14])=[O:12])=[C:9]([OH:17])[CH:8]=1

Participants

5

Reactant 2

HCID 21919190HCID 21919190, compoundHCID 178418361HCID 178418361, compound

Product 1

HCID 21919141HCID 21919141, compoundYield 97%

Reagents, catalysts & solvents 2

HCID 178418390HCID 178418390, compoundCatalystHCID 887MethanolSolvent

Procedure

Methyl 4-(3,4,5,6-tetramethoxy-2-methylbenzyl)-2-benzyloxybenzoate (530 mg, 1.1373 mmol) was dissolved in methanol (20 ml), added to a methanolic suspension (20 ml) of 10% palladium-carbon (100 mg) and stirred for 16 hours at room temperature in a hydrogen atmosphere. The reaction solution was filtered and the filtrate was concentrated under reduced pressure to give the title compound (414 mg, 1.101 mmol, 97%).

Workup

  1. filtrationThe reaction solution was filtered
  2. concentrationthe filtrate was concentrated under reduced pressure

Sources & evidence

ORD record
ord-9697c94361b74267b360774a048f9c55
Source dataset
uspto-grants-2006_10
Patent number
US07122543B2

Reaction notes

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