Hydrochloric Acid → HCID 10366114, compound

Participants

Reaction Steps

To a MeOH solution (0.6 mL) of methyl 2-[2-oxo-3-(3-{[7-propyl-3-(trifluoromethyl)-1,2-benzisoxazol-6-yl]oxy}propyl)imidazolidin-1-yl]propanoate as prepared in Example 40 (17.6 mg, 0.039 mmol), was added NaOH (0.6 mL, 0.154 mmol) and the mixture stirred at room temperature overnight. The reaction mixture was neutralized with 1N HCl and purified by preparative HPLC and the title compound was obtained.

Provenance & Evidence