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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1245352Generated: October 30, 2026

Dihydro-6-methyl-2,4(1H,3H)-pyrimidinedione → HCID 21911012, compound

https://huagongshe.com/reaction/1245352

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDihydro-6-methyl-2,4(1H,3H)-pyrimidinedioneHCID 97818—
Reactant3-Trifluoromethyl-7-propyl-6-(3-bromopropyloxy)-benzisoxazoleHCID 12031259—
ProductHCID 21911012HCID 21911012—

Reaction Steps

6-Methyl-3-(3-{[7-propyl-3-(trifluoromethyl)-1,2-benzisoxazol-6-yl]oxy}propyl)dihydropyrimidine-2,4(1H,3H)-dione was prepared as for Example 10 from 6-methyldihydropyrimidine-2,4(1H,3H)-dione and the bromide from Example 7. After aqueous work-up and silica gel chromatography, the title compound was obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07125865B2
Source datasetuspto-grants-2006_10
ORD IDord-dd6f558d00954e1ca7d495c5d6f688a1
Source noteuspto-grants-2006_10