HCID 59913127, compound → HCID 86592944, compound

Participants

Reaction Steps

Following a procedure analogous to that used in step 1c, but using 3-hydroxymethyl-but-3-enoic acid butyl ester from step 3a and 4-(2-methyl-quinolin-4-ylmethoxy)-benzaldehyde oxime from step 1b, the crude product was prepared. The product was purified by FCC on silica gel to give {5-formyl-3-[4-(2-methyl-quinolin-4-ylmethoxy)-phenyl]-4,5-dihydro-isoxazol-5-yl}-acetic acid butyl ester (0.13 g, 36%) as an oil. MS found: (M+H)+=461.

Provenance & Evidence