Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Sodium Cyanide | HCID 8929 | — |
| Reactant | HCID 55124806 | HCID 55124806 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 9795546 | HCID 9795546 | — |
Reaction Steps
Sodium cyanide (0.138 g) was added to a solution of the product from step (ii) (0.4 g) in N,N-dimethylformamide (20 ml) and heated at 90° C. for 16 h. The mixture was partitioned between ethyl acetate and water, a solid formed which was filtered off and purified by RPHPLC 15–85% acetonitrile in aqueous trifluoroacetic acid. Yield 0.05 g
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US07125881B2 |
|---|
| Source dataset | uspto-grants-2006_10 |
|---|
| ORD ID | ord-92dbbf2663404732949a2e5f21741e80 |
|---|
| Source note | uspto-grants-2006_10 |
|---|
