反应详情

Ethyl iodide (11.2 ml) was added dropwise to a stirred mixture of the product from step (i) (23 g) and sodium hydroxide (6 g) in water (400 ml). After 16 h the mixture was filtered, the filtrate acidified to pH1 and the precipitate filtered, washed with water and dried. Yield 17.8 g

1. filtrationAfter 16 h the mixture was filtered
2. filtrationthe precipitate filtered
3. washwashed with water
4. customdried