Di-tert-butyl Iminodicarboxylate → Di(tert-butyl) 3-cyanobenzylimidodicarbonate

HRID 1245443Notes

Reaction equation

HRID 1245443 reaction equation
Cl[CH2:2][C:3]1[CH:4]=[C:5]([CH:8]=[CH:9][CH:10]=1)[C:6]#[N:7].[NH:11]([C:19]([O:21][C:22]([CH3:25])([CH3:24])[CH3:23])=[O:20])[C:12]([O:14][C:15]([CH3:18])([CH3:17])[CH3:16])=[O:13]>>[C:6]([C:5]1[CH:4]=[C:3]([CH:10]=[CH:9][CH:8]=1)[CH2:2][N:11]([C:12]([O:14][C:15]([CH3:16])([CH3:17])[CH3:18])=[O:13])[C:19]([O:21][C:22]([CH3:25])([CH3:24])[CH3:23])=[O:20])#[N:7]

Participants

3

Reactant 2

HCID 279800Di-tert-butyl IminodicarboxylateHCID 5221263-(Chloromethyl)benzonitrile

Product 1

HCID 21930987Di(tert-butyl) 3-cyanobenzylimidodicarbonate

Procedure

) 3-(Chloromethyl)benzonitrile (30 g; 197.9 mmol) and di-tert-butyl iminodicarboxylate were reacted in analogy to Lila et al., Synth. Comm. 28, 23, 1998, 4419, to give di(tert-butyl) 3-cyanobenzylimidodicarbonate. 65 g of a reddish oil were obtained and were employed without further purification.

Sources & evidence

ORD record
ord-c4d609bb29c8458cb2217ade58ca1743
Source dataset
uspto-grants-2006_10
Patent number
US07125883B1

Reaction notes

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