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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1245584Generated: November 2, 2026

Hydrochloric Acid → HCID 131726000, compound

https://huagongshe.com/reaction/1245584

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantHCID 21912764HCID 21912764—
SolventMethanolHCID 887—
ProductHCID 131726000HCID 131726000—

Reaction Steps

To a solution of 1-(tert-Butoxycarbonyl)-4-(2-ethyl-4,5,6,7 tetrahydropyrazolo[1,5-a]pyridin-3-yl)-piperidine (1.41 g, from Step F) in MeOH (15 mL) was added a saturated HCl solution in MeOH (15 mL) at 0° C. After stirring at rt for 3 h, the reaction mixture was concentrated to give the title compound as a foamy solid, which was used without further purification.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07125887B2
Source datasetuspto-grants-2006_10
ORD IDord-6668b1a263234131996049af53fb89ad
Source noteuspto-grants-2006_10