HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 131726000, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | HCID 21912764 | HCID 21912764 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 131726000 | HCID 131726000 | — |
Reaction Steps
To a solution of 1-(tert-Butoxycarbonyl)-4-(2-ethyl-4,5,6,7 tetrahydropyrazolo[1,5-a]pyridin-3-yl)-piperidine (1.41 g, from Step F) in MeOH (15 mL) was added a saturated HCl solution in MeOH (15 mL) at 0° C. After stirring at rt for 3 h, the reaction mixture was concentrated to give the title compound as a foamy solid, which was used without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07125887B2 |
| Source dataset | uspto-grants-2006_10 |
| ORD ID | ord-6668b1a263234131996049af53fb89ad |
| Source note | uspto-grants-2006_10 |