Piperidine → HCID 21912702, compound

Participants

Reaction Steps

The title compound was prepared from 1-tert-butoxycarbonyl-4-(5-methyl-3-oxo-(1H)-pyrazol-4-yl)piperidine (Step C) using a procedure analogous to that described for Piperidine 15, Step D. RF: 0.34 (7:3 v/v hexanes/acetone); 1H-NMR (500 MHz) δ 1.47 (s, 9H), 1.57–1.59 (m, 2H), 1.75–1.83 (m, 2H), 2.16 (s, 3H), 2.44–2.50 (m, 1H), 2.70 (m, 2H), 3.86 (s, 3H), 4.17 (m, 2H); 13C-NMR (125 MHz) δ 55.8 (O—CH3).

Provenance & Evidence