Piperidine → 1-tert-Butoxycarbonyl-4-(1-ethyl-3-methoxy-5-methyl-(1H)-pyrazol-4-yl)piperidine

Participants

Reaction Steps

The title compound was prepared from 1-tert-butoxycarbonyl-4-(3-methoxy-5-methyl-(1H)-pyrazol-4-yl)piperidine (Step D) using a procedure analogous to that described for Piperidine 15, Step E. RF: 0.29 (9:1 v/v hexanes/acetone); 1H-NMR (500 MHz) δ 1.31 (t, J=7.3, 3H), 1.47 (s, 9H), 1.54–1.56 (m, 2H), 1.79–1.87 (m, 2H), 2.13 (s, 3H), 2.38–2.45 (m, 1H), 2.70 (m, 2H), 3.84 (s, 3H), 3.91 (q, J=7.3, 2H), 4.25 (m, 2H).

Provenance & Evidence