3-Chloro-2-methylbenzenesulfonyl chloride → HCID 9902066, compound

HRID 1245637Notes

Reaction equation

HRID 1245637 reaction equation
[CH2:1]([C:4]1[N:5]=[C:6]([NH2:9])[S:7][CH:8]=1)[CH2:2][CH3:3].[Cl:10][C:11]1[C:12]([CH3:21])=[C:13]([S:17](Cl)(=[O:19])=[O:18])[CH:14]=[CH:15][CH:16]=1>>[Cl:10][C:11]1[C:12]([CH3:21])=[C:13]([S:17]([NH:9][C:6]2[S:7][CH:8]=[C:4]([CH2:1][CH2:2][CH3:3])[N:5]=2)(=[O:19])=[O:18])[CH:14]=[CH:15][CH:16]=1

Participants

3

Reactant 2

HCID 5227343-Chloro-2-methylbenzenesulfonyl chlorideHCID 127798754-Propyl-2-thiazolamine

Product 1

HCID 9902066HCID 9902066, compoundYield 39%

Procedure

The title compound was prepared from 4-propyl-1,3-thiazol-2-ylamine (METHOD I) and 3-chloro-2-methylbenzenesulfonyl chloride according to METHOD A, yellow solid, 90 mg (39% yield): mp 169° C.; HRMS Calcd (found) for C13H15ClN2O2S2 M/Z 330.0263 (330.0251).

Sources & evidence

ORD record
ord-bbabb1fcce904aaca8998f147f08b9da
Source dataset
uspto-grants-2006_10
Patent number
US07125900B2

Reaction notes

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