Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1245648Generated: October 31, 2026

5-Acetyl-2-amino-4-methylthiazole → N-(5-acetyl-4-methyl-1,3-thiazol-2-yl)-4-propylbenzenesulfonamide

https://huagongshe.com/reaction/1245648

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Acetyl-2-amino-4-methylthiazoleHCID 720882—
Reactant4-N-Propylbenzenesulphonyl chlorideHCID 2737222—
ProductN-(5-acetyl-4-methyl-1,3-thiazol-2-yl)-4-propylbenzenesulfonamideHCID 11209950—

Reaction Steps

The title compound was prepared from 5-acetyl-2-amino-4-methylthiazole and 4-n-propylbenzenesulfonyl chloride as described in the synthetic METHOD B to give a white solid (11.6 mg) with purity >90%: MS (pos) m/z 339.2; HEMS m/z 338.0748 (calc. of monoisotopic mass for C15H18N2O3S2 gives 338.0759).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07125900B2
Source datasetuspto-grants-2006_10
ORD IDord-ffd26df12b0e45868fb94858c4f84bf9
Source noteuspto-grants-2006_10