2,6-Dichlorobenzenesulfonylchloride → HCID 11187666, compound

HRID 1245654Notes

Reaction equation

HRID 1245654 reaction equation
[C:1]([C:4]1[S:8][C:7]([NH2:9])=[N:6][C:5]=1[CH3:10])(=[O:3])[CH3:2].[Cl:11][C:12]1[CH:17]=[CH:16][CH:15]=[C:14]([Cl:18])[C:13]=1[S:19](Cl)(=[O:21])=[O:20]>>[C:1]([C:4]1[S:8][C:7]([NH:9][S:19]([C:13]2[C:14]([Cl:18])=[CH:15][CH:16]=[CH:17][C:12]=2[Cl:11])(=[O:21])=[O:20])=[N:6][C:5]=1[CH3:10])(=[O:3])[CH3:2]

Participants

3

Reactant 2

HCID 5221832,6-DichlorobenzenesulfonylchlorideHCID 7208825-Acetyl-2-amino-4-methylthiazole

Product 1

HCID 11187666HCID 11187666, compound

Procedure

The title compound was prepared from 5-acetyl-2-amino-4-methylthiazole (42 mg) and-2,6-dichlorobenzenesulfonyl chloride (66 mg) as described in the synthetic METHOD B to give a white solid (21.4 mg) with purity >90%: MS (pos) m/z 365.3, 367.3.

Sources & evidence

ORD record
ord-ecaaf6b164144becb8c77fb892249d59
Source dataset
uspto-grants-2006_10
Patent number
US07125900B2

Reaction notes

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