Piperidine → 5-Iodo-2-(1-piperidinyl)pyridine

HRID 1245790Notes

Reaction equation

Cl[C:2]1[CH:7]=[CH:6][C:5]([I:8])=[CH:4][N:3]=1.[NH:9]1[CH2:14][CH2:13][CH2:12][CH2:11][CH2:10]1>>[I:8][C:5]1[CH:6]=[CH:7][C:2]([N:9]2[CH2:14][CH2:13][CH2:12][CH2:11][CH2:10]2)=[N:3][CH:4]=1

Participants

Reactant 2

HCID 8082Piperidine

HCID 43971762-Chloro-5-iodopyridine

Product 1

HCID 447213585-Iodo-2-(1-piperidinyl)pyridine

Procedure

Prepared from 2-chloro-5-iodopyridine and piperidine by the method of Example 9 (d).

Sources & evidence

ORD record: ord-a3b5baad10634ac2b93bb489fee9b06e
Source dataset: uspto-grants-2006_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07125896B2

Reaction notes

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