Hydrochloric Acid → HCID 59338677, compound

Participants

Reaction Conditions

Reaction Steps

To a solution of 2-(2-ethoxy-naphthalen-1-yl)-3-methoxymethyl-3H-imidazole-4-carbaldehyde (prepared as described for 1-ethyl-2-naphthalen-1-yl-1H-imidazole-4-carbaldehyde illustrated in example 2.F) (2.4 g, 7.4 mmol) in dioxane (30 ml) is added 6.0 N hydrochloric acid (10 ml). The resulting mixture is stirred at 80° C. for 3 hr, and then cooled to rt. Dioxane is evaporated, and the residue is basified with 2.0N sodium hydroxide solution. The solid precipitate is collected, washed with water, dried under vacuum to give the title compound. LCMS 267 (M+1).

Provenance & Evidence